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Disease Reportsleft ventricular dysfunction
MeSH D018487 - left ventricular dysfunction
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Competitive Landscape
Events Timeline
Commercial
Clinical Trials
Competitive landscape
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D018754:Ventricular dysfunction
3 Companies
1 Drug
$
Success rate
D018487: 
Left ventricular dysfunction
91 Companies
28 Drugs
$
Success rate
D054549:Takotsubo cardiomyopathy
0 Companies
0 Drugs
Success rate
Events Timeline
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Commercial
Company Name
Drug Name
Trade Name
Patent Expires
Approval Date
Revenue
Period
AbbVieTrandolapril Mavik  1996-04-26   
Verapamil, Trandolapril Tarka  1996-10-22   
Hydrochlorothiazide, Eprosartan Teveten  2001-11-01   
Valsartan, Nebivolol Byvalson 2026-08-29 2016-06-03   
Accord HealthcareOlmesartan medoxomil, Amlodipine besylate Amlodipine Olmesartan Medoxomil  2018-08-30   
Lisinopril Lisinopril  2013-07-30   
Hydrochlorothiazide, Olmesartan medoxomil Olmesartan Medoxomil Hydrochlorothiazide  2019-02-07   
Ramipril Ramipril  2014-04-15   
Adhera TherapeuticsPerindopril arginine, Amlodipine besylate Prestalia 2023-04-15 2015-01-21   
Ajanta PharmaOlmesartan medoxomil, Amlodipine besylate Amlodipine Olmesartan Medoxomil  2016-10-28   
Captopril Captopril  2019-12-13   
Irbesartan Irbesartan  2015-12-10   
Alembic PharmaceuticalsValsartan, Amlodipine besylate Amlodipine Besylate Valsartan  2015-04-03   
Olmesartan medoxomil, Amlodipine besylate Amlodipine Olmesartan Medoxomil  2017-07-17   
Candesartan cilexetil Candesartan Cilexetil  2017-06-20   
Irbesartan Irbesartan  2012-10-15   
Irbesartan, Hydrochlorothiazide Irbesartan Hydrochlorothiazide  2012-10-15   
Losartan potassium Losartan Potassium  2010-10-06   
Hydrochlorothiazide, Losartan potassium Losartan Potassium Hydrochlorothiazide  2012-02-17   
Hydrochlorothiazide, Olmesartan medoxomil Olmesartan Medoxomil Hydrochlorothiazide  2017-04-24   
Telmisartan, Amlodipine besylate Telmisartan Amlodipine  2016-11-17   
Telmisartan, Hydrochlorothiazide Telmisartan Hydrochlorothiazide  2014-02-25   
Valsartan Valsartan  2015-01-05   
Hydrochlorothiazide, Valsartan Valsartan Hydrochlorothiazide  2013-03-21   
Alkem LaboratoriesOlmesartan medoxomil, Amlodipine besylate Amlodipine Olmesartan Medoxomil  2017-08-14   
Enalapril Enalapril  2022-03-30   
Valsartan Valsartan  2019-03-12   
AllerganTelmisartan, Hydrochlorothiazide Actelsar  2013-03-13   
Benazepril, Amlodipine besylate Amlodipine Besylate Benazepril  2010-10-14   
Captopril Captopril  1996-05-23   
Hydrochlorothiazide, Captopril Captopril Hydrochlorothiazide  1997-12-29   
Enalapril Enalapril  2000-08-22   
Irbesartan Irbesartan  2012-10-12   
Irbesartan, Hydrochlorothiazide Irbesartan Hydrochlorothiazide  2012-10-22   
Lisinopril Lisinopril  2002-07-01   
Hydrochlorothiazide, Lisinopril Lisinopril Hydrochlorothiazide  2002-07-01   
Losartan potassium Losartan Potassium  2010-10-06   
Hydrochlorothiazide, Losartan potassium Losartan Potassium Hydrochlorothiazide  2011-01-12   
Ramipril Ramipril  2005-10-24   
Trandolapril Trandolapril  2007-06-12   
Valsartan Valsartan  2015-01-05   
Hydrochlorothiazide, Valsartan Valsartan Hydrochlorothiazide  2013-03-21   
Almatica PharmaHydrochlorothiazide, Lisinopril Zestoretic  1989-07-20   
Amneal PharmaceuticalsBenazepril, Amlodipine besylate Amlodipine Besylate Benazepril  2018-12-07   
Enalapril Enalapril  2022-06-29   
Irbesartan Irbesartan  2018-04-17   
Valsartan Valsartan  2016-01-11   
Hydrochlorothiazide, Valsartan Valsartan Hydrochlorothiazide  2023-08-11   
ANI PharmaceuticalsCandesartan cilexetil, Hydrochlorothiazide Atacand  1998-06-04   
Hydrochlorothiazide, Benazepril Benazepril Hydrochlorothiazide  2004-02-11   
Hydrochlorothiazide, Fosinopril Fosinopril Hydrochlorothiazide  2004-12-03   
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Clinical Trials
Historical Success Rate
Phase 1
100%
1/1
Phase 2
33%
3/9
Phase 3
61%
17/28
Approved: 17Overall Success rate: 20%
All Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Company name
Phase 1
Phase 2
Phase 3
Phase 4
Drug Name
AbbVie
Hydrochlorothiazide
Allergan
Amlodipine besylate,
Hydrochlorothiazide,
Ramipril,
Valsartan
AstraZeneca
Enalapril,
Felodipine,
Enalaprilat,
Angiotensin ii,
Alpha1-proteinase inhibitor,
Spirolactone,
Ccb,
Lcz696,
Sglt2,
Farxiga,
AZD1305,
Betaloc,
Kcl
Aurobindo Pharma
Amlodipine besylate
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